Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1977328Generated: October 28, 2026

Methyl 2-hydroxy-3-phenylpropanoate → 2-[4'-(2-Benzyl-benzofuran-3-yl)-biphenyl-4-yloxy]-3-phenyl-propionic acid

https://huagongshe.com/reaction/1977328

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-hydroxy-3-phenylpropanoateHCID 518800—
Reactant4'-(2-Benzyl-benzofuran-3-yl)-biphenyl-4-olHCID 10547545—
Product2-[4'-(2-Benzyl-benzofuran-3-yl)-biphenyl-4-yloxy]-3-phenyl-propionic acidHCID 9914773—

Reaction Steps

The title compound was prepared from 4′-(2-benzyl-benzofuran-3-yl)-biphenyl-4-ol, and 3-phenyllactic acid methyl ester, in substantially the same manner, as described in Example 1, steps g-h , and was obtained as a white solid, mp 164-166° C.; MS m/e 524 (M+);

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06232322B1
Source datasetuspto-grants-2001_05
ORD IDord-93a639e26e014d8d859d64c21406032b
Source noteuspto-grants-2001_05