HuagongsheHuagongshe Chemistry Print Report · For research reference only
4'-(2-Benzyl-benzofuran-3-yl)-biphenyl-4-ol → (2S)-2-[4'-(2-benzyl-benzofuran-3-yl)-biphenyl-4-yloxy]-4-phenyl-butyric acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4'-(2-Benzyl-benzofuran-3-yl)-biphenyl-4-ol | HCID 10547545 | — |
| Reactant | (R)-(-)-2-hydroxy-4-phenylbutyric acid methyl ester | HCID 10878023 | — |
| Product | (2S)-2-[4'-(2-benzyl-benzofuran-3-yl)-biphenyl-4-yloxy]-4-phenyl-butyric acid | HCID 10602493 | — |
Reaction Steps
The title compound was prepared from 4′-(2-benzyl-benzofuran-3-yl)-biphenyl-4-ol, and (R)-(−)-2-hydroxy-4-phenylbutyric acid methyl ester, in substantially the same manner, as described in Example 1, steps g-h , and was obtained as a white solid, mp 152-154° C.; MS m/e 537 (M−H)+;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06232322B1 |
| Source dataset | uspto-grants-2001_05 |
| ORD ID | ord-2bbd6e0aa60041d6be3623e79166889f |
| Source note | uspto-grants-2001_05 |