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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1977347Generated: October 28, 2026

(S)-methyl 2-hydroxy-3-phenylpropanoate → (2S)-2-[4-(2-benzyl-benzofuran-3-yl)-4''-methoxy-[1,1';3',1'']terphenyl-4'-yloxy]-3-phenyl-propionic acid

https://huagongshe.com/reaction/1977347

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-methyl 2-hydroxy-3-phenylpropanoateHCID 5289077—
Reactant4-(2-Benzyl-benzofuran-3-yl)-4''-methoxy-[1,1';3',1'']terphenyl-4'-olHCID 10672435—
Product(2S)-2-[4-(2-benzyl-benzofuran-3-yl)-4''-methoxy-[1,1';3',1'']terphenyl-4'-yloxy]-3-phenyl-propionic acidHCID 9830685—

Reaction Steps

The title compound was prepared from 4-(2-benzyl-benzofuran-3-yl)-4″-methoxy-[1,1′;3′,1″]terphenyl-4′-ol, and (S)-(−)-3-phenyllactic acid methyl ester, in substantially the same manner, as described in Example 1, steps g-h , and was obtained as a white solid, mp 73-75° C.; MS m/e 629 (M−H)+;

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06232322B1
Source datasetuspto-grants-2001_05
ORD IDord-97def7a6d87349af9e4337855f9d0d14
Source noteuspto-grants-2001_05