Methyl iodide → Methyl 3-(benzyloxy)-5-methoxybenzoate

Participants

Reaction Steps

Following the procedure of Example 80(a) except substituting methyl 3-hydroxy-5-methoxybenzoate for methyl 3,5-dihydroxybenzoate and benzyl bromide for iodomethane, the title compound was prepared as a tan oil (1.2 g, 4.4 mmol). 1H NMR (400 MHz, CDCl3)δ7.45-7.31 (m, 6 H), 7.24 (s, 1 H), 6.76 (m, 1 H), 5.09 (s, 2 H), 3.95 (s, 3 H), 3.84 (s, 3 H).

Provenance & Evidence