1H-Isoindole-1,3(2H)-dione, 2-(2-bromoethyl)- → 1H-Isoindole-1,3(2H)-dione, 2-ethenyl-

Participants

Reaction Conditions

Reaction Steps

Over a period of 2 hours, 672 g of 1,8-diazabicyclo-[5.4.0]-undec-7-ene were added dropwise to a solution of 1016 g of N-(2-bromoethyl)phthalimide in 2.81 of N,N-dimethylacetamide. During the addition, the temperature increased to 60° C. After the addition had ended, stirring was continued for 12 hours. The batch was poured into 9 l of water and filtered, and the filtration residue was dried at 50° C. This gave 621 g of product (=90% of theory) of melting point 79-80° C.

Provenance & Evidence