Bromopentafluorobenzene → HCID 178505971, compound

Participants

Reaction Steps

Air inside a reaction vessel of the same type as the one used in Example 1 was replaced with a nitrogen gas in a satisfactory manner, after which 130 ml of a t-butyl methyl ether (chain ether solvent) solution containing 0.198 mol of suspended ethyl magnesium bromide as the hydrocarbon magnesium halide (2) was charged to the reaction vessel. Meanwhile, 0.182 mol of bromopentafluorobenzene was charged to the dropping funnel. Then, bromopentafluorobenzene in the dropping funnel was dropped to the reaction vessel over 45 minutes at room temperature, and the reaction solution was stirred for 4 hours at room temperature. Consequently, pentafluorophenyl magnesium bromide was obtained in the form of a colorless t-butylmethyl ether solution. The yield of pentafluorophenyl magnesium bromide measured in the same manner as Example 1 was 98.0 mol % based on bromopentafluorobenzene.

Provenance & Evidence