Methyl iodide → HCID 178505971, compound

Participants

Reaction Steps

Air inside a reaction vessel of the same type as the one used in Example 1 was replaced with a nitrogen gas in a satisfactory manner, after which 60 ml of a 1,2-dimethoxy ethane (chain ether solvent) solution containing 0.088 mol of suspended ethyl magnesium bromide was charged to the reaction vessel. Meanwhile, 0.081 mol of bromopentafluorobenzene was charged to the dropping funnel. Further, 0.5 g of methyl iodide was charged to the reaction vessel through a micro-syringe, and the reaction solution was stirred for 10 minutes at room temperature. Then, bromopentafluorobenzene in the dropping funnel was dropped to the reaction vessel over 45 minutes at room temperature, and the reaction solution was stirred for 4 hours at room temperature. Consequently, pentafluorophenyl magnesium bromide was obtained in the form of a colorless 1,2-dimethoxy ethane solution. The yield of pentafluorophenyl magnesium bromide measured in the same manner as Example 1 was 98.5 mol % based on bromopentafluorobenzene.

Provenance & Evidence