Butyl ether → Butyl ether

Participants

Reaction Conditions

Reaction Steps

Air inside a reaction vessel of the same type as the one used in Example 1 was replaced with a nitrogen gas in a satisfactory manner, after which 90 ml of a dibutyl ether (chain ether solvent) solution containing 0.188 mol of isopropyl magnesium bromide as the hydrocarbon magnesium halide (2) was charged to the reaction vessel. Meanwhile, 0.182 mol of bromopentafluorobenzene and 50 ml of dibutyl ether (chain ether solvent) were charged to the dropping funnel. Then, the dibutyl ether solution of bromopentafluorobenzene in the dropping funnel was dropped to the reaction vessel over 2 hours at room temperature, and the reaction solution was stirred for 2 hours at 35° C. Consequently, pentafluorophenyl magnesium bromide was obtained in the form of a light-yellow dibutyl ether solution. The yield of pentafluorophenyl magnesium bromide measured in the same manner as Example 1 was 97.5 mol % based on bromopentafluorobenzene.

Provenance & Evidence