HCID 21993392, compound → HCID 11066731, compound

Participants

Reaction Conditions

Reaction Steps

50.0 g (0.15 mol) of 2-methoxy-N-(4-nitrophenylsulfonyl)benzamide are suspended in a mixture of 450 ml of ethanol and 750 ml of 2N HCl, and the mixture is heated to 50° C. 97.2 g (1.5 mol) of zinc powder are added in portions at this temperature and the mixture is stirred for a further 2 hours. After cooling, the mixture is filtered, the filtrate is concentrated to half its volume and cooled, and the precipitate is filtered off with suction and dried; Yield: 43.6 g (96%); M.p.: 180-182° C.

Provenance & Evidence