Water → HCID 807748, compound

HRID 1977574Notes

Reaction equation

HRID 1977574 reaction equation
[S:1]([NH2:11])(=[O:10])([C:3]1[CH:8]=[CH:7][C:6]([NH2:9])=[CH:5][CH:4]=1)=[O:2].N1C=CC=CC=1.[CH3:18][O:19][CH2:20][C:21](Cl)=[O:22].O>O1CCOCC1>[CH3:18][O:19][CH2:20][C:21]([NH:9][C:6]1[CH:5]=[CH:4][C:3]([S:1](=[O:10])(=[O:2])[NH2:11])=[CH:8][CH:7]=1)=[O:22]

Participants

6

Reactant 4

HCID 962WaterHCID 1049PyridineHCID 5333SulfanilamideHCID 96623Methoxyacetyl chloride

Product 1

HCID 807748HCID 807748, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

10 g (0.06 mol) of sulfanilamide are suspended in 150 ml of dioxane and 4.6 g (60 mmol) of pyridine are added. 6.3 g (60 mmol) of methoxyacetyl chloride are then added at 0° C., and stirring is continued for 2 hours at room temperature. The mixture is stirred into 200 ml of water, and the precipitate which separates out is filtered off with suction and dried;

Workup

  1. filtrationthe precipitate which separates out is filtered off with suction
  2. customdried

Sources & evidence

ORD record
ord-5d28a6a3978e43b491da34129113c728
Source dataset
uspto-grants-2001_05
Patent number
US06235680B1

Reaction notes

Loading…