Isopropyl chloroformate → HCID 70118438, compound

Participants

Reaction Conditions

Reaction Steps

0.57 g (4 mmol) of 3-cyclobutyl-D-alanine is dissolved in 8 ml 1:1 mixture of 1M NaOH solution and dioxane. The mixture is cooled to 0° C. and simultaneously 4 ml of 1M NaOH solution and 4 ml of isopropyl chloroformate (conc. 1M in toluene) solution are added with vigorous stirring. The reaction mixture is stirred for 1 hour at this temperature and for 5 hours at room temperature.

Provenance & Evidence