HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Cyclohexanedione → HCID 21994440, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Cyclohexanedione | HCID 10434 | — |
| Reactant | 5-Amino-2-methoxyphenol | HCID 74314 | — |
| Catalyst | p-Toluenesulfonic acid | HCID 6101 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | HCID 21994440 | HCID 21994440 | 100.2% |
Reaction Steps
A solution of 1.00 g (7.19 mmole) of 3-hydroxy-4-methoxyaniline, 0.83 g (7.19 mmole) of 1,3-cyclohexanedione, and 50 mg of p-toluenesulfonic acid in 20 ml of benzene were heated reflux for 4.5 hours. The reaction solution was allowed to stand for one night at room temperature and the precipitated brown solid was collected by suction filtration. The crystal was washed with benzene, then was dried in vacuo to obtain 3-(3-hydroxy-4-methoxyanilino)-2-cyclohexen-1-one 1.68 g (yield 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06235736B1 |
| Source dataset | uspto-grants-2001_05 |
| ORD ID | ord-d6ec3dea548e4a4a81444f4b1202ce41 |
| Source note | uspto-grants-2001_05 |