HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Chloromethyl)pyridinium chloride → 3-[3-(2-indanyloxy)-4-methoxy-N-(4-pyridylmethyl)anilino]-2-methyl-2-cyclopenten-1-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Chloromethyl)pyridinium chloride | HCID 74570 | — |
| Reactant | 3-[3-(2-Indanyloxy)-4-methoxyanilino]-2-methyl-2-cyclopenten-1-one | HCID 9863185 | — |
| Product | 3-[3-(2-indanyloxy)-4-methoxy-N-(4-pyridylmethyl)anilino]-2-methyl-2-cyclopenten-1-one | HCID 21994450 | 38.8% |
Reaction Steps
According to the same procedure as in Example 28, using 3-[3-(2-indanyloxy)-4-methoxyanilino]-2-methyl-2-cyclopenten-1-one produced in Example 10 instead of 3-(3-cyclopentyloxy-4-methoxyanilino)-2-cyclopenten-1-one, and using 4-(chloromethyl)pyridine hydrochloride instead of methyl iodide, the title compound (yield 38.8%) was obtained as a brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06235736B1 |
| Source dataset | uspto-grants-2001_05 |
| ORD ID | ord-64ee173c34894fd386fa3d87085d74ed |
| Source note | uspto-grants-2001_05 |