HCID 135815251, compound → HCID 135815267, compound

HRID 1977624Notes

Reaction equation

HRID 1977624 reaction equation
[CH3:1][N:2]1[C:10]2[C:9](=[O:11])[NH:8][C:7]([CH2:12][C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([N+:19]([O-])=O)[CH:14]=3)=[N:6][C:5]=2[C:4]([CH2:22][CH2:23][CH3:24])=[N:3]1>[Pd]>[NH2:19][C:15]1[CH:14]=[C:13]([CH:18]=[CH:17][CH:16]=1)[CH2:12][C:7]1[NH:8][C:9](=[O:11])[C:10]2[N:2]([CH3:1])[N:3]=[C:4]([CH2:22][CH2:23][CH3:24])[C:5]=2[N:6]=1

Participants

3

Reactant 1

HCID 135815251HCID 135815251, compound

Product 1

HCID 135815267HCID 135815267, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

1-Methyl-5-(3-nitrobenzyl)-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-7-one (5.92 g, 0.019 mol) was suspended in industrial methylated spirit (300 ml). Palladium on charcoal (10%, 610 mg) was added and the resulting mixture was hydrogenated at 50 p.s.i and room temperature for 3 hours.

Sources & evidence

ORD record
ord-8108dd5aaf334239bc16a88bd8be8636
Source dataset
uspto-grants-2001_05
Patent number
US06235742B1

Reaction notes

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