Methanesulfonyl chloride → HCID 135815264, compound

HRID 1977625Notes

Reaction equation

HRID 1977625 reaction equation
[CH3:1][S:2](Cl)(=[O:4])=[O:3].[NH2:6][C:7]1[CH:27]=[CH:26][C:10]([CH2:11][C:12]2[NH:13][C:14](=[O:25])[C:15]3[N:20]([CH3:21])[N:19]=[C:18]([CH2:22][CH2:23][CH3:24])[C:16]=3[N:17]=2)=[CH:9][CH:8]=1>N1C=CC=CC=1>[CH3:21][N:20]1[C:15]2[C:14](=[O:25])[NH:13][C:12]([CH2:11][C:10]3[CH:26]=[CH:27][C:7]([NH:6][S:2]([CH3:1])(=[O:4])=[O:3])=[CH:8][CH:9]=3)=[N:17][C:16]=2[C:18]([CH2:22][CH2:23][CH3:24])=[N:19]1

Participants

4

Reactant 2

HCID 31297Methanesulfonyl chlorideHCID 1358152625-[(4-Aminophenyl)methyl]-1-methyl-3-propyl-1,4-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one

Product 1

HCID 135815264HCID 135815264, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

Methanesulfonyl chloride (43 μl, 0.00055 mol) was added to a solution of 5-(4-aminobenzyl)-1-methyl-3-propyl-6,7-dihydro-1H-pyrazolo[4,3-d]pyrimidin-7-one (150 mg, 0.0005 mol) in pyridine (5 ml), and the reaction stirred at room temperature, under a nitrogen atmosphere for 2 hours.

Sources & evidence

ORD record
ord-fd9b257609c54fc0bb85319f0ecf7894
Source dataset
uspto-grants-2001_05
Patent number
US06235742B1

Reaction notes

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