HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → N-(3,5-dimethoxyphenyl)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 3,5-Dimethoxyaniline | HCID 66301 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Solvent | Water | HCID 962 | — |
| Product | N-(3,5-dimethoxyphenyl)acetamide | HCID 702039 | — |
Reaction Steps
To a solution of 3,5-dimethoxyaniline (7.13 g, 46.5 mmol) in acetic acid (30 mL) and water (10 mL) was added acetic anhydride (4.61 mL, 48.9 mmol) at room temperature. The reaction was heated gently on a steam bath then cooled to room temperature. Excess water was added and the title compound 464A was collected by filtration.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06235740B1 |
| Source dataset | uspto-grants-2001_05 |
| ORD ID | ord-a8170a7293e04db5a3280fd8d715bf36 |
| Source note | uspto-grants-2001_05 |