HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetanilide → Acetamide, N-(m-methoxyphenyl)-N-phenyl-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetanilide | HCID 904 | — |
| Reactant | Benzene, 1-iodo-3-methoxy- | HCID 69839 | — |
| Product | Acetamide, N-(m-methoxyphenyl)-N-phenyl- | HCID 58591 | 67% |
Reaction Steps
Using acetanilide (3.7 g) and 3-iodoanisole, a reaction was made in the same manner as is 1) of Production Example 2. The subsequent purification by silica gel column chromatography (developing solvent, ethyl acetate:hexane=1:3 to 1:2) produced 3-methoxy-N-phenylacetanilide (4.44 g; yield, 67%) as a pale brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06235730B1 |
| Source dataset | uspto-grants-2001_05 |
| ORD ID | ord-f7783c372a0b4943b7418b85a7624bf7 |
| Source note | uspto-grants-2001_05 |