HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetanilide → N-(6-methyl-2-pyridyl)acetanilide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetanilide | HCID 904 | — |
| Reactant | 6-Chloro-2-picoline | HCID 87601 | — |
| Product | N-(6-methyl-2-pyridyl)acetanilide | HCID 21993566 | 7% |
Reaction Steps
Using acetanilide (9.16 g) and 2-chloro-6-methylpyridine (17.3 g), a reaction was made in the same manner as in 1) of Production Example 14. The subsequent purification by silica gel chromatography (developing solvent, ethyl acetate:hexane=1:1, ethyl acetate) produced N-(6-methyl-2-pyridyl)acetanilide (1.07 g; yield, 7%) as a pale brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06235730B1 |
| Source dataset | uspto-grants-2001_05 |
| ORD ID | ord-4bf9e1b3d0e24bc0b7a5e25de7e74f10 |
| Source note | uspto-grants-2001_05 |