HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromopyridine → 2-methoxy-N-(2-pyridyl)acetanilide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromopyridine | HCID 7973 | — |
| Reactant | 2-methoxy-N-phenylacetamide | HCID 264222 | — |
| Product | 2-methoxy-N-(2-pyridyl)acetanilide | HCID 21993568 | 58.6% |
Reaction Steps
Using 2-methoxy-acetanilide (5.0 g) and 2-bromopyridine (9.5 g), a reaction was made in the same manner as in 1) of Production Example 14. The subsequent purification by silica gel column chromatography (developing solvent, ethyl acetate: hexane=1:1) produced 2-methoxy-N-(2-pyridyl)acetanilide (4.3 g, crude product) as a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06235730B1 |
| Source dataset | uspto-grants-2001_05 |
| ORD ID | ord-162c1cd072634f41b05a44072b02e280 |
| Source note | uspto-grants-2001_05 |