HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 10638499, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Phenyl chloroformate | HCID 15891 | — |
| Reactant | 3-Fluoro-5-(pyridin-3-yl)aniline | HCID 15447787 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 10638499 | HCID 10638499 | 71.4% |
Reaction Steps
3-Fluoro-5-(pyrid-3-yl)aniline (1.05 g, 0.0050 mole) in dry dichloromethane was treated under argon with triethylamine (1.12 ml, 0.0080 mole) followed dropwise by phenyl chloroformate (0.97 ml, 0.0077 mole) and stirred at ambient temperature for 18 hours. The reaction mixture was washed (x2) with deionised water, dried (Na2SO4) and evaporated in vacuo to afford the title compound (1.1 g, 71%) as an off white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06235758B1 |
| Source dataset | uspto-grants-2001_05 |
| ORD ID | ord-5db4f48a46514f08aae6b1e9c132f3b3 |
| Source note | uspto-grants-2001_05 |