1,1'-Carbonyldiimidazole → HCID 18005158, compound

Participants

Reaction Steps

The title compound was prepared by the method of Example 23, from 4-(3-aminophenyl)isoquinoline (0.41 g, 1.9 mmol), 1,1′-carbonyldiimidazole (0.33 g, 2 mmol) and 5-methoxy-6-trifluoromethylindoline (D11) (0.41 g, 1.9 mmol). Crude product was chromatographed on silica gel eluted with 5% methanol/dichloromethane and eluted material was recrystallised from dichloromethane to give the title compound (0.22 g, 25%), m.p. 211-5° C.

Provenance & Evidence