HuagongsheHuagongshe Chemistry Print Report · For research reference only
Furan-2-boronic acid → 5-(2-Furyl)-pyrid-3-ylcarbamoyl-5-methoxy-6-trifluoromethylindoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Furan-2-boronic acid | HCID 2734357 | — |
| Reactant | HCID 10573917 | HCID 10573917 | — |
| Product | 5-(2-Furyl)-pyrid-3-ylcarbamoyl-5-methoxy-6-trifluoromethylindoline | HCID 86756710 | 80% |
Reaction Steps
This was prepared from 1-(5-bromopyrid-3-ylcarbamoyl)-5-methoxy-6-trifluoromethylindoline and 2-furylboronic acid by the same method as for Example 10, affording the title compound as a pale brown crystalline solid in 80% yield, m.p. 92-94° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06235758B1 |
| Source dataset | uspto-grants-2001_05 |
| ORD ID | ord-c982e59af9ff4b1f8157f249ced19c6c |
| Source note | uspto-grants-2001_05 |