2-(2-Aminoethyl)-1-methylpyrrolidine → HCID 10390019, compound

HRID 1977880Notes

Reaction equation

HRID 1977880 reaction equation
C1(O[C:8](=[O:30])[NH:9][C:10]2[S:14][N:13]=[C:12]([O:15][CH2:16][C:17]3[C:22]([F:23])=[CH:21][C:20]([CH3:24])=[C:19]([F:25])[C:18]=3[F:26])[C:11]=2[C:27](=[O:29])[NH2:28])C=CC=CC=1.[CH3:31][N:32]1[CH2:36][CH2:35][CH2:34][CH:33]1[CH2:37][CH2:38][NH2:39]>>[CH3:31][N:32]1[CH2:36][CH2:35][CH2:34][CH:33]1[CH2:37][CH2:38][NH:39][C:8](=[O:30])[NH:9][C:10]1[S:14][N:13]=[C:12]([O:15][CH2:16][C:17]2[C:22]([F:23])=[CH:21][C:20]([CH3:24])=[C:19]([F:25])[C:18]=2[F:26])[C:11]=1[C:27]([NH2:28])=[O:29]

Participants

3

Reactant 2

HCID 983882-(2-Aminoethyl)-1-methylpyrrolidineHCID 54053016[4-Carbamoyl-3-(2,3,6-trifluoro-4-methyl-benzyloxy)-isothiazol-5-yl]-carbamic acid phenyl ester

Product 1

HCID 10390019HCID 10390019, compound

Procedure

The title compound was prepared from [4-carbamoyl-3-(2,3,6-trifluoro-4-methyl-benzyloxy)-isothiazol-5-yl]-carbamic acid phenyl ester and 2-(1-methyl-pyrrolidin-2-yl)-ethylamine by the procedure analogous to Example 1. MS (APCI, m/z): 472 [M+H]+.

Sources & evidence

ORD record
ord-151d37a69a1045ee8e010c88d68aaef7
Source dataset
uspto-grants-2001_05
Patent number
US06235764B1

Reaction notes

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