HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Amino-1-piperidin-1-yl-pentan-2-ol → 5-[3-(4-Hydroxy-5-piperidin-1-yl-pentyl)-ureido]-3-(2,3,6-trifluoro-4-methyl-benzyloxy)-isothiazole-4-carboxylic acid amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Amino-1-piperidin-1-yl-pentan-2-ol | HCID 18549935 | — |
| Reactant | [4-Carbamoyl-3-(2,3,6-trifluoro-4-methyl-benzyloxy)-isothiazol-5-yl]-carbamic acid phenyl ester | HCID 54053016 | — |
| Product | 5-[3-(4-Hydroxy-5-piperidin-1-yl-pentyl)-ureido]-3-(2,3,6-trifluoro-4-methyl-benzyloxy)-isothiazole-4-carboxylic acid amide | HCID 10029921 | — |
Reaction Steps
The title compound was prepared from [4-carbamoyl-3-(2,3,6-trifluoro-4-methyl-benzyloxy)-isothiazol-5-yl]-carbamic acid phenyl ester and 5-amino-1-piperidin-1-yl-pentan-2-ol by the procedure analogous to Example 1. MS (APCI, m/z): 530 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06235764B1 |
| Source dataset | uspto-grants-2001_05 |
| ORD ID | ord-7e5a7b8b108845a7b7624820b9d9be21 |
| Source note | uspto-grants-2001_05 |