HCID 15523935, compound → HCID 10422082, compound

Participants

Reaction Steps

To a solution of (E)-1-[2-(acetylamino)ethylidene]-7-methoxy-1,2,3,4tetrahydronaphthalene (2.55 g, 10 mmol) in ethanol (20 ml) was added 5% palladium/carbon (50% hydrous, 400 mg). The mixture was subjected to catalytic reduction at normal pressure under hydrogen atmosphere. After the completion of hydrogenation, the palladium/carbon was then filtered off, and the solvent was distilled off under reduced pressure. The residue was purified by means of a silica gel column chromatography (chloroform:methanol=98:2) to give the above-titled compound (2.2 g, yield 86%, oil).

Provenance & Evidence