HCID 131722571, compound → HCID 21996067, compound

Participants

Reaction Conditions

Reaction Steps

A solution of Example 120B (1.59 g, 3.05 mmol) in 20 mL of dichloromethane at 0° C. was treated with trfluoroacetic acid (5 mL), stirred at 23° C. for 1 hour, concentrated, dissolved in ethyl acetate, washed with saturated NaHCO3 and brine, dried over Na2SO4, filtered, and concentrated. Purification on silica gel with 5% methanol/dichloromethane provided 820 mg (84%) of the desired product.

Provenance & Evidence