HCID 69944463, compound → HCID 69944055, compound

Participants

Reaction Steps

In an analogous manner to that described in Example 2, part (v), starting from 0.91 g of a mixture of 2(R)-[(S)-(carboxy)(cyclopentyl)methyl]-2′-isobutyl-2′-(methanesulphonyl)-4-methylvalerohydrazide and 2(R)-[(S)-(carboxy)(cyclopentyl)methyl]-2′-isobutyl-2′-(methanesulphonyl)-4-methyl-3-pentenohydrazide there was obtained 0.357 g of a mixture of 2(R)-[(S)-(cyclopentyl)[(tetrahydro-2(RS)-pyranyloxy)carbamoyl]methyl]-2′-isobutyl-2′-(methanesulphonyl)-4-methylvalerohydrazide and 2(R)-[(S)-(cyclopentyl)[(tetrahydro-2(RS)-pyranyloxy)carbamoyl]methyl]-2′-isobutyl-2′-2′-(methanesulphonyl)-4-methyl-3-pentenohydrazide in the form of a white solid.

Provenance & Evidence