反应详情

1 g (5.5 mmol) of methyl 3-methoxy-5-methylpyrazine-carboxylate was initially charged in 15 ml (198 mmol) of NH3 (25%) and the mixture was stied at 50° C. After concentration, 0.8 g of 3-methoxy-5-methylpyrazine-2carboxamide was obtained. The yield was 86 percent. Other data concerning the title product was:

1. customwas stied at 50° C
2. concentrationAfter concentration