Sodium borohydride → HCID 21707639, compound

HRID 1978257Notes

Reaction equation

[BH4-].[Na+].[CH3:3][C:4]1([C:16](=[O:18])[CH3:17])[CH2:6][CH:5]1[CH2:7][CH:8]1[CH2:12][CH:11]=[C:10]([CH3:13])[C:9]1([CH3:15])[CH3:14]>>[CH3:3][C:4]1([CH:16]([OH:18])[CH3:17])[CH2:6][CH:5]1[CH2:7][CH:8]1[CH2:12][CH:11]=[C:10]([CH3:13])[C:9]1([CH3:15])[CH3:14]

Participants

Reactant 2

HCID 4311764Sodium borohydride

HCID 21707624HCID 21707624, compound

Product 1

HCID 21707639HCID 21707639, compoundYield 53%

Procedure

Sodium borohydride reduction of 3.0 g (13.6 mmol) of 1-[1-methyl-2-(2,2,3-trimethyl-cyclopent-3-enylmethyl)cyclopropyl]ethanone from Example 12a according to Example 11b gave 1.6 g of 1-[1-methyl-2-(2,2,3-trimethylcyclopent-3-enylmethyl)cyclopropyl]ethanol (53% yield).

Sources & evidence

ORD record: ord-7589ff1e72b34b0fbce93ddcbb0d7283
Source dataset: uspto-grants-2001_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06235943B1

Reaction notes

Loading…