HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → HCID 21707640, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | Sulfoxonium, trimethyl-, iodide (1:1) | HCID 74498 | — |
| Reactant | HCID 53884120 | HCID 53884120 | — |
| Product | HCID 21707640 | HCID 21707640 | 35.1% |
Reaction Steps
13.0 g (60 mmol) of 2-[2-(2,2,3-trimethylcyclopent-3-enyl)ethylidene]-cyclopentanone was cyclopropanated with 16.2 g (74 mmol) of trimethyl-sulfoxonium iodide and 3.6 g (75 mmol) of 50% oil suspension of sodium hydride according to Example 11a to give 4.9 g (35% yield) of 1-(2,2,3-trimethylcyclopent-3-enylmethyl)spiro[2.4]heptan-4-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06235943B1 |
| Source dataset | uspto-grants-2001_05 |
| ORD ID | ord-21a9f8d537e44cf693b3382e48127e44 |
| Source note | uspto-grants-2001_05 |