Sodium hydride → HCID 21996667, compound

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Reaction Steps

NaH (60%, 0.273 g, 6.84 mmol), 33 (2.24 g, 3.11 mmol), and 1-iodopropane (0.67 mL, 6.9 mmol) in DMF (30 mL) were combined and worked up by the method of 43. Column chromatography (3:1 hexane/EtOAc) provided 2.01 g (80%) of 54 as an oil: NMR δ 0.71-0.78 (m, 6 H), 1.01-1.11 (m, 2 H), 1.34-1.48 (m, 12 H), 2.29 (s, 6 H), 2.57-2.58 (2 s, 18 H), 2.98-3.13 (m, 12 H), 6.92 (s, 6 H). Anal. (C42H65N3O6S3.H2O) C, H, N.

Provenance & Evidence