Iodoethane → HCID 10747861, compound

Participants

Reaction Steps

NaH (80%, 0.52 g, 17 mmol), 34 (3.2 g, 4.36 mmol), and iodoethane (1.5 g, 9.6 mmol) in DMF (20 mL) were reacted and worked up by the method of 43. Column chromatography (4:1 hexane/EtOAc) gave 2.91 g (85%) of 56 as a white solid: mp 60-62° C.; NMR δ 1.01 (t, 6 H, J=7), 1.08 (m, 4 H), 1.42 (m, 8 H), 2.29 (s, 9 H), 2.57 (s, 6 H), 2.58 (s, 12 H), 3.07 (t, 4 H, J=7), 3.11 (t, 4 H, J=7), 3.17 (q, 4 H), 6.92 (s, 6 H). Anal. (C41H63N3O6S3) C, H, N.

Provenance & Evidence