Sodium hydride → HCID 10843119, compound

Participants

Reaction Steps

NaH (80%, 198 mg, 6.6 mmol), 34 (1.51 g, 2.06 mmol), and 1-iodopropane (0.44 mL, 4.5 mmol) in DMF (40 mL) were reacted and worked up by the method of 43. Column chromatography (7:2/hexane/EtOAc) provided 1.61 g (95%) of 57 as an oil: NMR δ 0.75 (t, 6 H, J=7), 1.02-1.14 (m, 4 H), 1.36-1.52 (m, 12 H), 2.30 (s, 9 H), 2.60 (s, 18 H), 3.02-3.16 (m, 12 H), 6.95 (s, 6 H). Anal. (C43H67N3O6S3) C, H, N.

Provenance & Evidence