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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 197835Generated: October 30, 2026

Hydrochloric Acid → 4-[4-(4-Ethyl-5-fluoro-2-methoxyphenoxy)-3-fluorobenzoyl]piperazin-2-one

https://huagongshe.com/reaction/197835

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantDimethylformamideHCID 6228—
ReactantDichloromethaneHCID 6344—
ReactantOxalyl chlorideHCID 65578—
ReactantDiisopropylethylamineHCID 81531—
ReactantPiperazin-2-oneHCID 231360—
Reactant4-(4-Ethyl-5-fluoro-2-methoxyphenoxy)-3-fluorobenzoic acidHCID 67116046—
Product4-[4-(4-Ethyl-5-fluoro-2-methoxyphenoxy)-3-fluorobenzoyl]piperazin-2-oneHCID 67116248—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-c2c3bd4dd90e40309e407857bde5b016
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)