Hydrogen chloride-ethyl acetate → HCID 21993703, compound

Participants

Reaction Steps

To a solution of 580.0 mg (1.2 mM) of N-[3-(1-(3-(2-chlorophenyl)propan-1-yl)piperidin-4-yl)propan-1-yl]-5-thia-1,8b-diazaacenaphthylene-4-carboxamide in ethanol (10 ml) was added 2 ml (8.0 mM) of 4N-HCl/ethyl acetate and the mixture was stirred for several minutes. The solvent was then distilled off under reduced pressure and ether was added to the residue. The resulting crystal crop was harvested by filtration and rinsed with ethanol and diethyl ether to provide the title compound as orange-colored crystals (605.4 mg, 91%).

Provenance & Evidence