反应详情

To a solution of 347 mg (0.8 mM) of N-[1-(3-(2-fluorophenyl)propan-1-yl)piperidin-4-ylmethyl]-5-thia-1,8b-diazaacenaphthylene-4-carboxamide in ethanol (4 ml) was added 1.0 ml (4.0 mM) of 4N-HCl/methanol. After the solvent was distilled off under reduced pressure, ethanol and diethyl ether were added to the residue and the resulting crystals were collected by filtration and rinsed with ethanol and diethyl ether to provide the title compound.

1. distillationAfter the solvent was distilled off under reduced pressure, ethanol and diethyl ether
2. additionwere added to the residue
3. filtrationthe resulting crystals were collected by filtration
4. washrinsed with ethanol and diethyl ether