HCID 21993984, compound → 5-Thia-1,8b-diazaacenaphthylene-4-carbaldehyde

HRID 1978503Notes

Reaction equation

HRID 1978503 reaction equation
[N:1]1[CH:2]=[C:3]2[N:12]3[C:7](=[CH:8][CH:9]=[CH:10][C:11]=13)[S:6][C:5]([CH2:13][OH:14])=[CH:4]2>C(Cl)(Cl)Cl.[O-2].[O-2].[Mn+4]>[N:1]1[CH:2]=[C:3]2[N:12]3[C:7](=[CH:8][CH:9]=[CH:10][C:11]=13)[S:6][C:5]([CH:13]=[O:14])=[CH:4]2

Participants

4

Reactant 1

HCID 21993984HCID 21993984, compound

Product 1

HCID 219941445-Thia-1,8b-diazaacenaphthylene-4-carbaldehyde

Reagents, catalysts & solvents 2

HCID 178418406HCID 178418406, compoundCatalystHCID 6212ChloroformSolvent

Procedure

To a solution of 1.073 g (5.253 mM) of 5-thia-1,8b-diazaacenaphthylene-4-methanol in 30 ml of chloroform was added 3 g of activated manganese dioxide (Aldrich) and the mixture was stirred at room temperature for 4 hours. This reaction mixture was filtered and the filter cake was washed with chloroform. The filtrate and washes were pooled and the solvent was distilled off under reduced pressure. The crude 5-thia-1,8b-diazaacenaphthylene-4-carbaldehyde thus obtained was not purified but used as it was in the next reaction.

Workup

  1. filtrationThis reaction mixture was filtered
  2. washthe filter cake was washed with chloroform
  3. distillationthe solvent was distilled off under reduced pressure

Sources & evidence

ORD record
ord-e8259484c79a4632a98412e63dc8f543
Source dataset
uspto-grants-2001_05
Patent number
US06235731B1

Reaction notes

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