Hydrochloric Acid → HCID 21994055, compound

Participants

Reaction Steps

To a solution of 1.56 g (3.28 mmol.) of N-[2-(2,6-dioxo-4-(3-phenylpropan-1-yl)piperazin-1-yl)ethan-1-yl]-5-thia-1,8b-diazaacenaphthylene-4-carboxamide in ethanol (10 ml) was added, at room temperature, 2 ml (24 mmol.) of 12N hydrochloric acid. The mixture was stirred for several minutes, which was concentrated under reduced pressure to leave crystals. To the crystals was added ethanol, which was subjected to filtration to collect the crystals. The crystals was washed with ethanol and diethyl ether to give the object compound as an orange crystalline product. The yield was 1.20 g (66%).

Provenance & Evidence