HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(2-Methoxyphenyl)piperazine → 1-(2-Methoxyphenyl)-4-[3-(benzoyl)-3-(phenyl)butyl]piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(2-Methoxyphenyl)piperazine | HCID 1346 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Reactant | 3-Benzoyl-3-phenylbutyraldehyde | HCID 12051066 | — |
| Product | 1-(2-Methoxyphenyl)-4-[3-(benzoyl)-3-(phenyl)butyl]piperazine | HCID 15524029 | 23.4% |
Reaction Steps
Following the procedures described in the Example 1, Step C, the reaction of 3-benzoyl-3-phenylbutyraldehyde (0.32 g) and 1-(2-methoxyphenyl)piperazine (0.23 g) with sodium triacetoxyboranehydride (0.33 g) gave pure product 1-(2-methoxyphenyl)-4-[3-(benzoyl)-3-(phenyl)butyl]piperazine (0.12 g). The oxalate salt was prepared as described above.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06239135B1 |
| Source dataset | uspto-grants-2001_05 |
| ORD ID | ord-d8be6583cb5a4a4eaae101c9e71b3232 |
| Source note | uspto-grants-2001_05 |