反应详情

28 g of tert-butyl 3-amino-3-(4-trifluoromethyl-3-pyridinecarbonyloxyimino)propionate are dissolved in 380 ml of toluene and heated under reflux for 17 hours. Concentration and chromatographic purification of the residue over silica gel gives 14.4 g of the product as a pale brown oil.

1. temperatureheated
2. temperatureunder reflux for 17 hours
3. concentrationConcentration and chromatographic purification of the residue over silica gel