HuagongsheHuagongshe Chemistry Print Report · For research reference only
Carbon Tetrachloride → 2-Bromo-1-(4-fluorophenyl)-2-(4-(methylsulfonyl)phenyl)ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Carbon Tetrachloride | HCID 5943 | — |
| Reactant | Chloroform | HCID 6212 | — |
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 1-(4-Fluorophenyl)-2-(4-methylsulfonylphenyl)ethanone | HCID 11243301 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2-Bromo-1-(4-fluorophenyl)-2-(4-(methylsulfonyl)phenyl)ethanone | HCID 11234079 | — |
Reaction Steps
To 1-(4-Fluorophenyl)-2-(4-(methylsulfonyl)phenyl)ethanone (1.00 g) in CH2Cl2 containing CHCl3 (1.0 mL) and CCl4 (1.0 mL) was added bromine (0.614 g). After shining light for 1 h, the reaction was quenched with Na2S2O4, extracted with CH2Cl2, dried over Na2SO4 and evaporated to yield the title compound which was used as such for the next step (1.10 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06239173B1 |
| Source dataset | uspto-grants-2001_05 |
| ORD ID | ord-f996f8879680474ab9cedafb16dc634d |
| Source note | uspto-grants-2001_05 |