HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Methoxide → HCID 11469378, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | HCID 18400184 | HCID 18400184 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 11469378 | HCID 11469378 | 96.4% |
Reaction Steps
A solution of 8 g of 1-(4-fluorophenyl)-5-oxo-2-pentanone in 300 mL of MeOH was treated with 2 g of NaOMe. The mixture was stirred for 2 h and then quenched with 5 mL of HOAc. The solvent was evaporated and the residue purified by flash chromatography, eluting with 3:1 hexane/EtOAc to give 7 g of the title product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06239173B1 |
| Source dataset | uspto-grants-2001_05 |
| ORD ID | ord-7fab2fcd9ab84d7fa296c7a6d5585b14 |
| Source note | uspto-grants-2001_05 |