HCID 20658002, compound → HCID 86756922, compound

HRID 1979224Notes

Reaction equation

HRID 1979224 reaction equation
C(OC(N[C@@H](C([N:16]([CH2:46][CH:47]([CH3:49])[CH3:48])[NH:17][C:18](=[O:45])[C@@H:19]([CH:24]([C:34](=[O:44])NOCC1C=CC=CC=1)[CH2:25][CH2:26][CH2:27]C1C=CC=CC=1)[CH2:20][CH:21]([CH3:23])[CH3:22])=O)C)=O)C1C=CC=CC=1.[C:50]([O:54]C(C([C@@H](CC(C)C)C(O)=O)CC=C)=O)([CH3:53])([CH3:52])[CH3:51]>>[C:50]([O:54][C:34]([CH:24]([C@@H:19]([CH2:20][CH:21]([CH3:22])[CH3:23])[C:18]([NH:17][NH:16][CH2:46][CH:47]([CH3:48])[CH3:49])=[O:45])[CH2:25][CH:26]=[CH2:27])=[O:44])([CH3:53])([CH3:52])[CH3:51]

Participants

3

Reactant 2

HCID 20658002HCID 20658002, compoundHCID 86756905HCID 86756905, compound

Product 1

HCID 86756922HCID 86756922, compound

Procedure

In an analogous manner to that described in Example 1, part (i), but using 2(R)-[1(RS)-(tert-butoxycarbonyl)-3-butenyl]-4-methylvaleric acid in place of (E)-2(R)-[1(S)-(tert-butoxycarbonyl)-4-phenyl-3-butenyl]-4-methylvaleric acid there was obtained 2(R)-[1(RS)-(tert-butoxycarbonyl)-3-butenyl]-2′-isobutyl-4-methylvalerohydrazide as a yellow oil.

Sources & evidence

ORD record
ord-bfff173ba6b44d49bea9084e61c03772
Source dataset
uspto-grants-2001_05
Patent number
US06239151B1

Reaction notes

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