(Phenylmethyl)hydrazine → 2'-benzyl-2(R)-[4-cyclohexyl-1(S)-[(tetrahydro-2(RS)-pyranyloxy)carbonyl]butyl]-2'-[2-(1,2,3-triazol-1-yl)acetyl]valerohydrazide

Beteiligte Stoffe

Reaktionsschritte

In a manner analogous to that described in Example 1, parts (iii)-(vii) and Example 8, from 2(R)-[1(S)-(tert-butoxycarbonyl)-4-cyclohexylbutyl]-4-methylvaleric acid and benzylhydrazine and using 1,2,3-triazole-1-acetic acid in place of N-tert.butoxycarbonyl-β-alanine in Example 8, there was obtained 2′-benzyl-2(R)-[4-cyclohexyl-1(S)-[(tetrahydro-2(RS)-pyranyloxy)carbonyl]butyl]-2′-[2-(1,2,3-triazol-1-yl)acetyl]valerohydrazide in the form of a white solid.

Herkunft & Nachweise