Imidazole-1-acetic acid → HCID 86756933, compound

Participants

Reaction Steps

In a manner analogous to that described in Example 8 from (E)-2(R)-[1(S)-(benzyloxycarbamoyl)-4-phenyl-3-butenyl]-4-methyl-2′-(2(S)-methylbutyl)valerohydrazide and using imidazole-1-acetic acid in place of N-tert-butoxycarbonyl-β-alanine in Example 8 there was obtained (E)-2(R)-[1(S)-(benzyloxycarbamoyl)-4-phenyl-3-butenyl]-2′-[2-(1H-imidazol-1-yl)acetyl]-4-methyl-2′-(2(S)-methylbutyl)valerohydrazide in the form of a gum.

Provenance & Evidence