Trifluoroacetic acid → HCID 86756937, compound

Participants

Reaction Steps

A solution of 0.050 g of (E)-2(S)-amino-3-[[2-[2(R)-[1(S)-(hydroxycarbamoyl)-4-phenyl-3-butenyl]-4-methylvaleryl]-1-isobutylhydrazino]carbonyl]tert.butoxypropionate hydrogen chloride in 1 ml of dichloromethane was treated with 0.400 mL of trifluoroacetic acid. The mixture was stirred for 4 hours at room temperature and evaporated. The residue was triturated with diethyl ether, filtered off and dried to give 0.022 g of (E)-2(S)-amino-3-[[2-[2(R)-[1(S)-(hydroxycarbamoyl)-4-phenyl-3-butenyl]-4-methylvaleryl]-1-isobutylhydrazino]carbonyl]propionic acid trifluoroacetate in the form of a white solid.

Provenance & Evidence