(E)-2(R)-[1(S)-[(tetrahydro-2(RS)-pyranyloxy)-carbamoyl]-4-phenyl-3-butenyl]-2'-isobutyl-4-methylvalerohydrazide → HCID 86756955, compound

Participants

Reaction Steps

A solution of 1.0 g of (E)-2(R)-[1(S)-[(tetrahydro-2(RS)-pyranyloxy)carbamoyl]-4-phenyl-3-butenyl]-2′-isobutyl-4-methylvalerohydrazide in 20 ml of methanol was hydrogenated in the presence of 0.100 g of 5% palladium-on-carbon for 0.5 hours. The catalyst was removed by filtration and the solvent was evaporated to give 0.93 g of 2(R)-[1(S)-[(tetrahydro-2(RS)-pyranyloxy)carbamoyl]-4-phenylbutyl]-2′-isobutyl-4-methylvalerohydrazide in the form of a white solid.

Provenance & Evidence