p-Toluenesulfonic acid monohydrate → HCID 131722589, compound

Participants

Reaction Steps

A solution of 0.210 g of 2′-(D-alanyl)-2(R)-[5-cyclohexyl-1(RS)-[(tetrahydro-2(RS)-pyranyloxy)carbamoyl]pentyl]-2′-isobutyl-4-methylvalerohydrazide in 5 ml of methanol was treated with 0.080 g of p-toluenesulphonic acid monohydrate. The mixture was stirred at room temperature for 6 hours and evaporated. The residue was triturated with diethyl ether to give 0.151 g of 2′-D-alanyl)-2(R)-[5-cyclohexyl-1(RS)-(hydroxycarbamoyl)pentyl]-2′-isobutyl-4-methylvalerohydrazide p-toluenesulphonate in the form of a white solid.

Provenance & Evidence