反应详情

In 10 ml. of pyridine was dissolved 2.9 g. of the product obtained in Example 17, and to the solution was added 1.1 g. of acetic anhydride under stirring. The resulting mixture was then refluxed for 1 hour. The reaction mixture was then poured into 50 ml. of water, and was then extracted with n-hexane. The extract was washed with water and dried. The solvent was removed by evaporation. The residual oily product was purified by silica gel column chromatography to obtain 3.1 g. of the desired oily product.

1. temperatureThe resulting mixture was then refluxed for 1 hour
2. additionThe reaction mixture was then poured into 50 ml
3. extractionof water, and was then extracted with n-hexane
4. washThe extract was washed with water
5. customdried
6. customThe solvent was removed by evaporation
7. customThe residual oily product was purified by silica gel column chromatography
8. customto obtain 3.1 g