Acetamidine monohydrochloride → HCID 178467223, compound

HRID 1979808Notes

Reaction equation

HRID 1979808 reaction equation
Cl[CH:2]([CH:6]1OCCO1)[C:3](=[O:5])[CH3:4].Cl.[C:12]([NH2:15])(=[NH:14])[CH3:13].C([O-])(=O)C.[Na+]>C(O)(C)(C)C>[C:3]([C:2]1[N:14]=[C:12]([CH3:13])[NH:15][CH:6]=1)(=[O:5])[CH3:4]

Participants

5

Reactant 3

HCID 67170Acetamidine monohydrochlorideHCID 517045Sodium AcetateHCID 13376668HCID 13376668, compound

Product 1

HCID 178467223HCID 178467223, compound

Reagents, catalysts & solvents 1

HCID 6386tert-ButanolSolvent

Procedure

A mixture of 1.64 g (10 mmole) 2-(1-chloro-2-oxopropyl)dioxolane, 1.89 g (20 mmole) acetamidine hydrochloride, 2.46 g (30 mmole) sodium acetate and 20 ml t-butanol is heated at reflux for 24 hours and the product isolated as in Part A.

Workup

  1. temperatureis heated
  2. temperatureat reflux for 24 hours
  3. customthe product isolated as in Part A

Sources & evidence

ORD record
ord-0e4d2d354d8c4fcaa1f1ca1dca198561
Source dataset
uspto-grants-1984_11
Patent number
US04482723

Reaction notes

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